Opto-Electronic Engineering
Opto-Electronic EngineeringPrevious  
Vol. 46, No. 4, 2019
Cover Story:Yin L J, Rao Y J, Dai J H, et al. A feasibility study of using fiber-optic Raman spectrum system for fast diagnosis of gastric cancer[J]. Opto-Electronic Engineering, 2019, 46(4): 180645

Raman spectra can be used for molecular analysis of the structure because of the rule of molecular vibration and rotation. This technology is fast, simple, trace, repeatable, nondestructive and almost not affected by the interference of water, so that it is especially suitable for the research in the field of medicine. The molecular changes within Cancer cells can produce characteristic Raman spectra. Spectral differences including displacement, the intensity and the number of peak show that the vibration of the cancer molecular chemical bond, functional group within the organization changed, so as to explore the change of molecular configuration conformation in the cancer tissue, the relative content and existing state.
Professor Peng Guiyong team from Institute of Digestive Disease of Army Medical University committed to the study of Raman spectra of the gastrointestinal tumors and built a optical fiber Raman system matching with the endoscopic examination.They used the system to detect the Raman spectrum of gastric mucosa and gastric adenocarcinoma and compared the ratio of integral energy of continuous band and non -continuous band. Compared with the traditional pathology diagnosis method, Fiber Raman spectroscopy system provided a new method for clinical diagnosis research on the gastrointestinal tumors. This method could be called ’optical biopsy’ to some extent.
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Yin Lijian, Rao Yunjiang, Dai Jianhua, et al. A feasibility study of using fiber-optic Raman spectrum system for fast diagnosis of gastric cancer[J]. Opto-Electronic Engineering, 2019, 46(4): 180645.