Adaptive optics (AO) techniques allow to measure and manipulate the wavefront aberrations in real time. This technology was first successfully applied to the manipulation of ocular aberrations, and high resolution retinal images and "supernormal vision" were achieved in vivo for the first time in 1997. Subsequently, adaptive optics were developed rapidly in ophthalmology. This field includes two main directions: high resolution imaging of the retina and the research of ocular aberrations manipulation and its influence on visual function. In 2011, professor D. R. Williams from Rochester University and Professor Austin Roorda from California University made two comprehensive overviews on retinal high-resolution imaging and ocular aberrations manipulation and its influence on visual function, respectively. In 1997, reseachers in Institute of Optics and Electronics took the lead in developing of adaptive optics technology in China. This article firstly introduces the principle of ocular adaptive optical system briefly, and then reports the main research progress of Institute of Optics and Electronics in this field for the last five years.
Ocular aberrations manipulation with adaptive optics and its application
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21 Zhao J L. Objective assessment of ocular scatter and its influence on visual function[D]. Chengdu: Institute of Optics and Electronics, Chinese Academy of Sciences, 2017.
22 Zhao J L, Xiao F, Kang J, et al. Quantifying intraocular scatter with near diffraction-limited double-pass point spread function[J]. Biomedical Optics Express, 2016, 7(11): 4595-4604. DOI:10.1364/BOE.7.004595
23 Zhao J L, Xiao F, Zhao H X, et al. Effect of higher-order aberrations and intraocular scatter on contrast sensitivity measured with a single instrument[J]. Biomedical Optics Express, 2017, 8(4): 2138-2147. DOI:10.1364/BOE.8.002138
24 Xiao F, Zhao J L, Zhao H X, et al. Deblurring adaptive optics retinal images using deep convolutional neural networks[J]. Biomedical Optics Express, 2017, 8(12): 5675-5687. DOI:10.1364/BOE.8.005675
Supported by the National Natural Science Foundation of China (61205202, 61378064), National High Technology Research and Development Program of China (2015AA020510), National Scientific Instrumentsand Equipment De-velopment Special Foundation of China (2012YQ120080, 2013YQ49085903) and Instrument Developing Project of the Chinese Academy of Sciences (y2010028)
Get Citation: Dai Yun, Xiao Fei, Zhao Junlei, et al. Ocular aberrations manipulation with adaptive optics and its application[J]. Opto-Electronic Engineering, 2018, 45(3): 170703.
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