Proteins are a class of biomaterials having a vast array of functions, including the catalysis of metabolic reactions, DNA replication, stimuli response and transportation of molecules. Recent progress in laser-based fabrication technologies has enabled the formation of three-dimensional (3D) proteinaceous micro- and nano-structures by femtosecond laser cross-linking, which has expanded the possible applications of proteins. This article reviews the current knowledge and recent advancements in the femtosecond laser cross-linking of proteins. An overview of previous studies related to fabrication using a variety of proteins and detailed discussions of the associated mechanisms are provided. In addition, advances and applications utilizing specific protein functions are introduced. This review thus provides a valuable summary of the 3D micro- and nano-fabrication of proteins for biological and medical applications.
Fabrication of three-dimensional proteinaceous micro- and nano-structures by femtosecond laser cross-linking (From OEA, Vol.1, No.4)
First published at:Mar 01, 2019
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RIKEN SPDR program,The Amada Foundation Research Grant (Jyuten-Kenkyu-Kaihatsu-Josei A)
Get Citation: Serien D, Sugioka K. Fabrication of three-dimensional proteinaceous micro- and nano-structures by femtosecond laser cross-linking[J]. Opto-Electronic Advances, 2018, 1(4): 180008.
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