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Overview: The vessel enhancement for medical endoscopic images can provide more details of blood vessels, which is useful for assisting doctors in diagnosis. An enhancement method based on multi-color spatial nonlinear contrast stretching is proposed in the present study, which is able to effectively perform vessel enhancement for endoscopic images in real time.
In the proposed method, the contrast stretching for enhancement is successively carried out for the G (Green) component in RGB color space and the S (Saturation) component in HSV color space. Since the details in G component are usually clearer than those in R (Red) and B (Blue) component for the endoscopic tissue images, the contrast stretching for G component only can more effectively enhance the vessels in the tissue. And the contrast stretch for S component can make the color of vessels brighter than that of tissue, which is suitable to the human visual system.
First, the G component is mapped by a nonlinear mode for contrast stretching. The mapping parameter is determined by that the value with maximum contrast stretching effect in the nonlinear mode is equal to the average value of G component of image. Then, the color space of image is converted from RGB to HSV and the S component is mapped by a nonlinear mode same to the G component. Similarly, the mapping parameter of S component is determined by that the value with maximum contrast stretching effect is equal to the average value of S component of image. Finally, the enhanced image is obtained by converting the HSV data with enhanced S component to RGB color space.
The above algorithm was implemented by a C# program and its enhancement effect was tested by multiple endoscopic vessel images. The experiment results show that even very small vessels which are almost invisible in the original images can be seen in the enhanced images under the suitable mapping parameter determined by the proposed method. The enhanced images are also compared with those obtained by FICE and Spectral-B, which are normal enhancement methods in their respective endoscopes. It is showed that only our enhancement images have consistent color tone with the original images and the DVs (detail variances) of our enhancement images are significantly larger than those obtained by FICE or Spectral-B. The enhancement algorithm was embedded in the program for an endoscope with a resolution of 1280 pixels×800 pixels, and the video speed with enhancement effect was tested to reach 26 fps on a computer with the 2.7 GHz CPU and 3.2 G memory.
Molar extinction coefficients of human hemoglobin[12]
Endoscopic images. (a) Original color images; (b) Red component images; (c) Green component images; (d) Blue component images
Flow chart of vascular enhancement algorithm
Gray mapping function curve with different d values
Comparison of enhancement effects under different parameters
Comparison of effects under different enhancement methods
Oral endoscopic enhancement image sequence