Du S, Zhang C L, Sun W M, et al. Application of laser microfabrication in medical equipment[J]. Opto-Electron Eng, 2023, 50(3): 220306. doi: 10.12086/oee.2023.220306
Citation: Du S, Zhang C L, Sun W M, et al. Application of laser microfabrication in medical equipment[J]. Opto-Electron Eng, 2023, 50(3): 220306. doi: 10.12086/oee.2023.220306

Application of laser microfabrication in medical equipment

    Fund Project: Anhui Natural Science Foundation - General Program (1908085ME130), Key Programs of Natural Science Foundation of Anhui University (KJ2019A0791), and Anhui Province's Key Areas of Manufacturing Industry in 2021: Production, Research and Research of Complementary Products and Key Common Technologies (JB21096)
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  • Laser microfabrication has the characteristics of ultra fast, ultra precision, etc. It has unique advantages in the field of medical equipment by contrast with traditional processing technology. Especially, it plays an irreplaceable role in the surface processing of biological materials to improve the biocompatibility of materials. The latest application of laser microfabrication in the field of medical equipment manufacturing and processing in recent years is reviewed. The structure and surface manufacturing of vascular stents and bone stents, and the surface modification of biomaterials and antibacterial treatment are emphatically introduced. Finally, the limitations of the current laser micromachining technology are discussed, and the application and development of laser micromachining technology in medical equipment in the future are prospected.
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  • In recent years, the manufacturing industry has been developing in the direction of precision and high precision. In order to improve machining accuracy, scholars at home and abroad have carried out a lot of research on micro-machining. As a high-precision, green, and environment-friendly non-contact processing technology, laser processing has good flexibility and controllability. Because of its high accuracy, fast speed, small damage, and high power density, it has a broad application prospect in the biomedical field. Laser micro-processing technology endows biomaterials with new structures and functions, fully mobilizes the human body's self-repair ability, and realizes the permanent rehabilitation of damaged tissues or organs, which has become the development direction of contemporary biomedical science.

    In order to systematically demonstrate the achievements of laser micromachining technology in the field of biomedicine, this paper analyzes the advantages of laser micromachining in the precision forming and surface modification of medical components from the manufacturing process and surface microstructure of medical devices, and summarizes the latest progress of laser micromachining technology in the manufacturing and processing of typical biomedical components. The influence of surface microstructures on the biocompatibility and antibacterial properties of medical components was explored. Furthermore, the achievements of laser micro-processing technology in the field of medical equipment manufacturing were systematically demonstrated.

    Finally, the limitations of laser processing at present are summarized, and the application and development of laser micromachining technology in the field of medical equipment in the future are prospected. Although laser micro-processing technology can micro-process a new generation of implantable medical devices with extremely fine structure, making the commercial use of the next generation of implantable medical devices feasible, the development of laser micro-processing technology in the biomedical field is not mature enough, the production efficiency is low, and the work stability needs to be improved. For the laser micromachining process, a complete set of theories has not yet been formed to explain the physical nature of the interaction between the laser and material under the extreme conditions of ultra-fast, ultra-short, and ultra-strong, nor can the impact of laser micromachining on the material structure and physical and chemical properties be well evaluated. The next work still needs a lot of basic and regular research. At the same time, according to the characteristics of laser micromachining and the properties of the processed materials, it is also necessary to develop simulation analysis software to simulate the micromachining process and optimize the parameters of the laser micromachining process.

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