Cover Story： Yin Lijian, Rao Yunjiang, Dai Jianhua, et al. A feasibility study of using fiber-optic Raman spectrum system for fast diagnosis of gastric cancer[J]. Opto-Electronic Engineering, 2019, 46(4): 180645. 

Cells canceration originates from a series of physiological and biochemical changes, such as nucleic acid synthesis, the fracture of side chain, the change of the cell structure and the relative content of protein and the increased liquidity of cell membrane, etc. The molecular changes within cancer cells can generate changes in characteristic Raman spectra. Spectral differences including displacement, the intensity and the number of peak show that the vibration of the cancer molecular chemical bond, functional group within the organization changed, so as to explore the changes of molecular configuration conformation in the cancer tissue, the relative content and existing state. Professor Peng Guiyong’ group from Institute of Digestive Disease of Army Medical University committed to the study of Raman spectra of the gastrointestinal tumors and built a optical fiber Raman system equipped with an endoscopic examination.